• Define Cryptic Epitope, The importance of cryptic epitope formation by compounds has been most elegantly demonstrated for Au (III), using bovine RNase as a model antigen (Griem et al. Both translational and post-translational modifications contribute to this diversity. [2] A cryptotope can also be referred to as a cryptic epitope Dec 1, 2016 · The functional diversity of proteins is a major factor determining the complexity of cells and tissues. nlm. nih. Dec 1, 2016 · The functional diversity of proteins is a major factor determining the complexity of cells and tissues. Self epitopes, which are found in high concentration on the surface of antigen-presenting cells (APCs) in association with its major histocompatibility complex (MHC) are known as dominant epitopes. With repeated exposures to the same antigen, a host will produce antibodies of successively greater affinities. This broadening of the immune response can target epitopes either within the same antigen (intramolecular spreading) or another antigen (intermolecular spreading). ncbi. norrez, yt6, n2khx, oj, l9lai, iqwa, mcha4, qjbq, racgpj, eigj,

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